Alan van Giessen

Assistant Professor of Chemistry

Joined the faculty in 2008

Postdoctoral, University of Leiden
Postdoctoral, Boston University
Ph.D. 1999, Cornell University
M.S 1996, Cornell University
B.S. 1994 Purdue University

Read Alan van Giessen's Curriculum Vitae

Courses Routinely Taught:
Physical Chemistry I, Thermodynamics (CHEM 320)
Physical Chemistry II, Quantum Mechanics (CHEM 322)
Intermediate General Chemistry (CHEM 280)
Introduction to General Chemistry (CHEM 110)

Current scholarly interests:
Effects of macromolecular crowding on protein folding, misfolding, and aggregation
Determining aggregation pathways for amyloidogenic proteins
Structural and energetic properties of curved interfaces
Development of novel multicanonical simulation algorithms

Current Research Students:
Andrew Baird '14
Matthew Church '14
Christine Ferry '14

Recent Peer-Reviewed Publications:
(student authors in bold)

M.S. Church, C.E. Ferry, and A.E. van Giessen "Thermodynamics of peptide dimer formation" J. Chem. Phys. 136M, 245102 (2012).

A.E. van Giessen and E.M. Blokhuis, "Direct determination of the Tolman length from the bulk pressures of liquid s via molecular dynamics simulations" J. Chem. Phys. 131, 164705 (2009).

External Grants:
Cottrell College Science Award
American Chemical Society Petroleum Research Fund

Professional Affiliations:
Member, American Chemical Society
Member Biophysical Society
Member, Sigma Xi

Research Description:
I am interested in applying my extensive background in physical chemistry to complex computational biophysical problems. My main interest is in studying the effects of macromolecular crowding on protein folding, misfolding and aggregation. I have a long-held interest in thermodynamics and statistical mechanics, both of which are essential tools for describing any physical system. I am particularly interested in how molecular properties lead to large-scale, macroscopic or mesoscopic phenomena, and in questions related to scale and how phenomena on different scales interact.

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