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Erin Pelkey

Professor of Chemistry

Joined the faculty in 2001

Postdoctoral, Stanford University
Ph.D., Dartmouth College
B.A., Carleton College

Read Erin Pelkey's Curriculum Vitae

Pelkey Research Group


Courses Routinely Taught:
Organic Chemistry I (CHEM 240)
Organic Chemistry II (CHEM 241)

Courses Occasionally Taught:
Advanced Organic Chemistry (CHEM 447)
Introduction to General Chemistry (CHEM 110)

Current Scholarly Interests:
Heterocyclic chemistry
Total synthesis of biologically active natural products
Metal-mediated tandem reactions

Current Research Students:
Amy Van Loon '14
Maeve Holton '15
Carly Rolph '15

Recent Peer-Reviewed Publications:
(Note: HWS Undergraduate co-authors in bold)

Greger, J.G.; Yoon-Miller, S.J.P.; Bechtold, N.R.; Flewelling, S.A.; MacDonald, J.P.; Downey, C.R.; Cohen, E.A.; Pelkey, E.T. Synthesis of Unsymmetrical 3,4-Diaryl-3-pyrrolin-2-ones Utilizing Pyrrole Weinreb Amides. J. Org. Chem. 2011, 76, 8203-8214.

Yoon-Miller, S.J.P. Dorward, K.M. White, K.P. Pelkey, E.T. Suzuki-Miyaura Arylations of Tetramic Acid Sulfonates: Evaluation of Lactam Protection, Sulfonate Esters, and Sterics. J. Heterocycl. Chem. 2009, 46, 447-454.

Dorward, K.M. Guthrie, N.J. Pelkey, E.T. Suzuki-Miyaura Cross-Coupling Approach to 3,4-Diaryl-3-pyrrolin-2-ones from Tetramic Acid Triflates. Synthesis 2007, 2317-2322.

Yoon-Miller, S.J.P. Opalka, S.M. Pelkey, E.T. Short Synthesis of 4-Aryl-3-pyrrolin-2-ones. Tetrahedron Lett. 2007, 48, 827-830.

Coffin, A.R. Roussell, M.A. Tserlin, E. Pelkey, E.T. Regiocontrolled Synthesis of Pyrrole-2-carboxaldehydes and 3-Pyrrolin-2-ones from Pyrrole Weinreb Amides. J. Org. Chem. 2006, 71, 6678-6681.

Recent Book Chapters:
(Note: HWS Undergraduate co-authors in bold)

Russel, J.; Pelkey, E.T.; Greger, J.G. Five-Membered Ring Systems: Pyrroles and Benzo Derivatives. In Progress in Heterocyclic Chemistry, Gribble, G.W. and Joule, J.A., Eds.; Elsevier Science: New York, 2011, 23, 155-194.

Pelkey, E.T. Metalation of Indole. In Topics in Heterocyclic Chemistry. Gribble G.W., Ed.; Heterocyclic Scaffolds I: Indole; Springer-Verlag: Berlin, 2010, in press.

Russel, J.; Pelkey, E.T.; Yoon-Miller, S.J.P. Five-Membered Ring Systems: Pyrroles and Benzo Derivatives. In Progress in Heterocyclic Chemistry, Gribble, G.W. and Joule, J.A., Eds.; Elsevier Science: New York, 2010, 22, in press.

Russel, J. Pelkey, E.T. Yoon-Miller, S.J.P. Five-Membered Ring Systems: Pyrroles and Benzo Derivatives. In Progress in Heterocyclic Chemistry, Gribble, G.W. and Joule, J.A., Eds. Elsevier Science: New York, 2009, 21, 145-178.

Pelkey, E.T. Selenophenes. In Comprehensive Heterocyclic Chemistry III, Katritzky, A.R. Ramsden, C.A. Scriven, E.F.V. Taylor, R., Eds. Elsevier: Oxford, 2008 Vol. 3, 975-1006.

Russel, J. Pelkey, E.T. Five-Membered Ring Systems: Pyrroles and Benzo Derivatives. In Progress in Heterocyclic Chemistry, Gribble, G.W. and Joule, J.A., Eds. Elsevier Science: New York, 2008, 20, 122-151.

Pelkey, E.T. Russel, J. Five-Membered Ring Systems: Pyrroles and Benzo Derivatives. In Progress in Heterocyclic Chemistry,, Gribble, G.W. and Joule, J.A., Eds. Elsevier Science: New York, 2007, 19, 135-175.

Pelkey, E.T. Five-Membered Ring Systems: Pyrroles and Benzo Derivatives. In Progress in Heterocyclic Chemistry, Gribble, G.W. and Joule, J.A., Eds. Elsevier Science: New York, 2006, 18, 150-186.

External Grants:
National Institute of Health Academic Research Enhancement Award (NIH-AREA) #1R15-GM086819-01A1, $197,648 (2009-2012): "New Methodology for the Synthesis of Highly Functionalized Nitrogen Heterocycles"

National Science Foundation #1044396, $180,000 (2011-2014): "TUES: Transforming Cell Biology and Organic Chemistry through Incorporation of the HDACi Cancer Therapeutic Lab Project" (with Miller, Carle, and Mowery)

National Science Foundation #0722178, $342,000 (2007-2010): "MRI: Acquisition of an NMR Spectrometer to Maintain Active Undergraduate Education and Research Programs" (with Miller and de Denus)

ACS-Petroleum Research Fund, Type G, $35,000 (2004-2007): "Development of Tandem Metal Mediated Cyclization Reactions for the Total Synthesis of Alkaloid Natural Products"

Research Corporation Cottrell Scholar, $46,018 (2003-2005): "Regiocontrolled Synthesis of Complex Pyrrole Heterocycles"

Camille and Henry Dreyfus Start-Up Grant, $20,000 (2001-2006): "New Synthetic Approach to Staurosporine Derivatives, Potent Inhibitors of Protein Kinase C"

Awards:
Hobart and William Smith Colleges Faculty Teaching Prize (2006-2007)
NIH Postdoctoral Fellowship (1999-2001)
ACS Division of Organic Chemistry Graduate Fellowship (1997-1998)
Honorable Mention, NSF Predoctoral Fellowship (1994)
Richard W. Ramette Teaching Award, Carleton College (1993-1994)

Professional Activities:
Member, American Chemical Society
Member, International Society of Heterocyclic Chemistry
Reviewer, Tetrahedron Letters
Reviewer, Tetrahedron
Reviewer, Synthesis
Reviewer, ARKIVOC
Reviewer, Petroleum Research Fund
Reviewer, Research Corporation
Reviewer, National Science Foundation
Reviewer, National Institute of Health
Board of Observers, Muhlenberg Chemistry Department (2013)

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